Semiconductors play a vital role in modern life, serving as the backbone of nearly all electronic devices—from smartphones and computers to solar panels and medical equipment. As the demand for smaller, faster, and more efficient devices grows, semiconductor nanowires have emerged as a promising frontier. These ultra-thin structures offer unique electrical, optical, and mechanical properties, potentially enabling breakthroughs in areas like quantum computing, ultra-sensitive sensors, flexible electronics, and next-generation transistors. This talk will present a summary of our research on core/shell III-V semiconductor nanowires, highlighting their unique potential for strain engineering and tailoring of electronic properties, as well as the significant challenges associated with their fabrication.